Characteristics

The functional group is an amino group;

Ultra-acid sensitive, and cleavage can be completed under extremely mild conditions of 1% TFA.

Commonly used is Sieber resin with the amino group protected by Fmoc. When loading the first amino acid, Fmoc needs to be removed first. The steric hindrance of this packing is smaller than that of Rink resin, so it has more advantages than Rink resin in synthesizing peptides containing amino acids with large steric hindrance.

Applications

Compared with Rink resin, Sieber Amide is not only suitable for synthesizing C-terminal amidated peptides but also for synthesizing partially protected peptide amide fragments, having more advantages in synthesizing peptides with special functions.

Physical and chemical Performance Indicators

Parameter	Indicator
Appearance	White to light yellow microspheres
Particle Size Range (mesh)	100～200
Substitution Degree (mmol/g)	0.3～1.0
Loss on Drying (%)	≤2.0
Swelling Degree (mL/g)	DCM 4.5～10.0 DMF 4.0～8.0

Have Any Questions?

If you have any questions, please don't hesitate to contact us. We're always here to help with ion exchange resins for your business. Haipu is able to produce the product in according to your special needs.

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+86-18915626237