Simulated Moving Bed Chromatography - Jiangsu Haipu Functional Materials Co.,Ltd.

Simulated Moving Bed (SMB) is a highly efficient, continuous chemical separation process that separates binary or pseudo-binary mixtures into pure substances or fractions.

In a Simulated Moving Bed (SMB) system, the chromatographic column is divided into four functional zones, each of which can be further subdivided into smaller zones. By periodically switching all inlets and outlets simultaneously to the adjacent right-hand position, the movement of the solid adsorbent to the left can be simulated. Compared with traditional preparative chromatography methods, the SMB process can significantly improve the purification yield of the target substance and reduce the consumption of eluent and packing material.

Equipment Advantages

Highly Efficient Washing	Environmental Protection and Emission Reduction	Stable Feed	Precise Self-control
Through serial column washing technology, the conversion from low concentration to high concentration is realized, avoiding water carrying materials and ensuring the resin exchange capacity.	Make full use of regenerants, reduce consumption, reduce water consumption, and reduce wastewater discharge.	The multi-column parallel feed system reduces system fluctuations during switching and maintains stable effluent pH.	Valve array control realizes cross-column operation, fully automatic operation reduces human error, and ensures stable product quality.

Typical Applications

Pharmaceutical industry: chiral separation, antibiotic separation, purification of proteins and peptides, separation of nucleotides and nucleosides, separation of drug metabolites, etc.
Food chemistry: separation of fatty acids, purification of vitamins, separation of sweeteners, pigment extraction, etc.
Separation of isomers: fructose/glucose, D-allulose/fructose, mannitol/sorbitol, tryptophan/isoleucine, etc.
Separation of oligomers: fructooligosaccharides, galactooligosaccharides, fiber sugar, resistant dextrin, lactulose, propylene glycol polymers.
Separation of organic molecules and salts: separation and purification of various organic acids, amino acids, polyols, such as glycine, methionine, 1,3-propanediol, etc.
Petrochemical industry: separation of normal/isoalkanes, p-xylene/other xylene isomers, m-xylene/other xylene isomers.
Biochemistry: Separation of organic and inorganic acids/salts, such as citric acid, tartaric acid monoesters/diesters, succinic acid monoacids/polyacids, etc.

Here to Provide Complete Separation and Purification Solutions

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