Fixed Enzyme Carrier Resin Material

Fixed enzymes are a series of advantages such as immobilizing enzymes on a carrier for repeated use, simple process, and low cost. At present, enzymes with high storage stability, easy separation and recovery, and multiple applications in the chemical industry, materials science, environmental protection, energy, proteomics, and other fields have been widely used in the pharmaceutical and food industries. It has a very broad development prospect.

Characteristics of immobilized enzyme resin carrier

1. Has high physical and chemical stability

2. Has low expansibility in high concentration solutions and conventional solvents

3. Dense cross-linking to give it excellent mechanical permeability

4. Easy to recycle and reuse

5. It has biological affinity and compatibility, which is conducive to the active expression of enzyme activity

6. With a high enzyme loading capacity, the carrier surface can provide multiple active sites, which is conducive to enzyme molecule coupling

Different pore sizes can be selected according to the needs of biocatalysis

1. For proteins with larger molecular weights, larger pore size resins should be selected

2. The smaller the pore size of the resin, the larger the surface area, and the higher the fixation capacity

3. Resins with smaller pore sizes can provide better mechanical stability

Aperture

Porosity	Aperture (nm)	Dry weight (%)	Volume (mL/g)	Protein (kDa)
Level l	10-20	35-45	2.8-3.3	<100
Level l	20-50	35-45	2.9-3.4	<100
Level l	40-60	30-40	3.5-3.7	80-250

Appropriate immobilization techniques

Porosity	Functional group	Covalent linkage		Adsorbent
Porosity	Functional group	Direct connection	Active group	Adsorbent
EP	Epoxy based	Yes	-	-
HFA	Long interval arm epoxy group	Yes	-	-
EA，HA	Amino	-	Glutaraldehyde, Dialdehyde	Electrostatic interaction
HG	Hydroxyl group	-	NaIO₄	Hydrophilic interaction
QA	Quaternary amino group	-	-	Electrostatic interaction
BU	Alkyl group	-	-	Hydrophobic interaction
0D	Alkyl group	-	-	Hydrophobic interaction

Product Line

Innovative Materials Technology/Service Energy Metals/Leading the Resource Cycle

Service Process

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