Synthesis Ion Exchange Resin Carriers

Solid-Phase Peptide Synthesis (SPPS) Supports

Solid-phase peptide synthesis (SPPS), a revolutionary technology pioneered by Merrifield, has emerged as an indispensable tool in biochemistry and drug discovery since its inception. Since the 1960s, SPPS has fundamentally driven leaps in peptide and protein synthesis technology, owing to its exceptional performance in efficiently synthesizing predetermined peptide chains with guaranteed purity and product homogeneity. This has exerted profound impacts on drug design, bioprobe development, and fundamental life science research.

The solid support plays a pivotal role in SPPS, serving as the stable interface for peptide chain construction, the primary site for synthetic reactions, and the medium for final target peptide release. After decades of development, solid support materials have evolved from initial polystyrene resins to diversified systems, including functionalized resins such as polystyrene-divinylbenzene resins and polymethacrylate resins. Through sophisticated design of chemical functional groups and structural optimization, these materials have significantly enhanced the controllability of the synthesis process and the diversity of synthetic products

Immobilized Enzyme Carriers

Immobilized enzyme technology refers to fixing enzymes onto carriers to facilitate catalytic reactions. Free enzymes can be immobilized on the surface or within the interior of carriers through chemical or physical methods, which enhances enzyme activity and stability during recycling and enables efficient recovery. Commonly used enzymes in the market include hydrolases (e.g., lipase, laccase, amylase, pectinase, cellulase, microbial enzyme, dehydrogenase, etc.), transaminases, and isomerases. Compared with free enzymes, immobilized enzymes offer a series of advantages, such as high storage stability, easy separation and recovery, repeatable use, simple process, and low cost. Currently, immobilized enzymes have been widely applied in pharmaceutical fields, food industry, chemical industry, materials science, environmental protection, energy sector, proteomics, etc., demonstrating broad development prospects.

Types of Synthesis Carriers

Sieber Resin

Sieber resin is used for synthesizing peptide amides and is widely applied in peptide drug production due to its unique functional group side chain structure that effectively avoids side reactions.
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Rink Amide MBHA Resin

Rink Amide MBHA resin is a commonly used solid-phase peptide synthesis support, with application fields similar to those of Rink Amide AM.
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HP-2CTC Resin

HP-2CTC resin is a polymer used for solid-phase peptide synthesis. In solid-phase peptide synthesis, it bonds with the carboxyl end of amino acids through functional groups to allow peptide chain grow...
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HP-Wang Resin

Wang resin is currently the most widely used solid-phase peptide synthesis resin, which can be used for the immobilization of carboxyl and phenolic hydroxyl groups in solid-phase synthesis. After este...
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HP-Rink Amide AM Resin

HP-Rink Amide AM resin is a support resin for solid-phase peptide synthesis, modified from aminomethyl polystyrene resin via a Rink amide linker. Treatment with 95% trifluoroacetic acid enables cleava...
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HP-DETA200——Immobilized Enzyme Carrier

HP-DETA200 is a long-chain polyamino-modified resin material serving as an enzyme immobilization carrier.
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HP-EA200——Immobilized Enzyme Carrier

HP-EA200 is a short-chain amino-modified resin material serving as an enzyme immobilization carrier.
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HP-HA200——Immobilized Enzyme Carrier

HP-HA200 is a long-chain amino-modified resin material serving as an enzyme immobilization carrier.
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Maximize Profits with High-Demand Synthesis Carriers

Solid-Phase Peptide Synthesis (SPPS) Supports

Immobilized Enzyme Carriers

Types of Synthesis Carriers